Impact of combining data from multiple instruments on performance of patient-based real-time quality control     

Qianqian Zhou  Tze Ping Loh  Tony Badrick  Chun Yee Lim 《Biochemia medica : ?asopis Hrvatskoga dru?tva medicinskih biokemi?ara / HDMB》2021,31(2)

IntroductionIt is unclear what is the best strategy for applying patient-based real-time quality control (PBRTQC) algorithm in the presence of multiple instruments. This simulation study compared the error detection capability of applying PBRTQC algorithms for instruments individually and in combination using serum sodium as an example.Materials and methodsFour sets of random serum sodium measurements were generated with differing means and standard deviations to represent four simulated instruments. Moving median with winsorization was selected as the PBRTQC algorithm. The PBRTQC parameters (block size and control limits) were optimized and applied to the four simulated laboratory data sets individually and in combination.ResultsWhen the PBRTQC algorithm were individually optimized and applied to the data of the individual simulated instruments, it was able to detect bias several folds faster than when they were combined. Similarly, the individually applied algorithms had perfect error detection rates across different magnitudes of bias, whereas the error detection rates of the algorithm applied on the combined data missed smaller biases. The performance of the individually applied PBRTQC algorithm performed more consistently among the simulated instruments compared to when the data were combined.DiscussionWhile combining data from different instruments can increase the data stream and hence, increase the speed of error detection, it may widen the control limits and compromising the probability of error detection. The presence of multiple instruments in the data stream may dilute the effect of the error when it only affects a selected instrument.  相似文献   

Impaired motor control after sport-related concussion could increase risk for musculoskeletal injury: Implications for clinical management and rehabilitation     

Terese L. Chmielewski  Justin Tatman  Shuhei Suzuki  MaryBeth Horodyski  Darcy S. Reisman  Russell M. Bauer  James R. Clugston  Daniel C. Herman 《运动与健康科学(英文)》2021,10(2):154

This review presents a conceptual framework and supporting evidence that links impaired motor control after sport-related concussion (SRC) to increased risk for musculoskeletal injury. Multiple studies have found that athletes who are post-SRC have higher risk for musculoskeletal injury compared to their counterparts. A small body of research suggests that impairments in motor control are associated with musculoskeletal injury risk. Motor control involves the perception and processing of sensory information and subsequent coordination of motor output within the central nervous system to perform a motor task. Motor control is inclusive of motor planning and motor learning. If sensory information is not accurately perceived or there is interference with sensory information processing and cognition, motor function will be altered, and an athlete may become vulnerable to injury during sport participation. Athletes with SRC show neuroanatomic and neurophysiological changes relevant to motor control even after meeting return to sport criteria, including a normal neurological examination, resolution of symptoms, and return to baseline function on traditional concussion testing. In conjunction, altered motor function is demonstrated after SRC in muscle activation and force production, movement patterns, balance/postural stability, and motor task performance, especially performance of a motor task paired with a cognitive task (i.e., dual-task condition). The clinical implications of this conceptual framework include a need to intentionally address motor control impairments after SRC to mitigate musculoskeletal injury risk and to monitor motor control as the athlete progresses through the return to sport continuum.  相似文献   

动作发展视域下幼儿足球促进粗大动作发展水平研究     

孙启成  刘金富  朱小烽 《浙江体育科学》2020,(3):57-63

探讨幼儿足球对幼儿粗大动作发展水平的影响,为干预幼儿粗大动作发展提供依据。选取嘉兴市108名5~6岁幼儿为受试对象,以班级为单位随机分为干预组与对照组。干预组进行12周幼儿足球游戏活动教学,2次*40min/周;对照组幼儿为静态性的课堂班级活动。干预前后采用PGMQS测量幼儿位移能力、操控能力及平衡能力。采用独立样本t检验、配对样本t检验及协方差分析两组幼儿前后测结果的差异性。结果显示:①干预前,两组幼儿粗大动作发展水平无显著性差异(P>0.05);干预后,两组幼儿粗大动作发展水平存在显著性差异(P<0.05),干预组高于对照组。②干预组和对照组幼儿后测结果与前测结果间均存在显著性差异(P<0.05),后测结果高于前测。研究结果表明幼儿粗大动作发展存在延长效应,但结构化幼儿足球游戏活动明显提高了幼儿粗大动作发展水平。因此建议抓牢幼儿早期动作发展的敏感期,以动作发展为主线科学设计幼儿足球游戏活动并保证活动的顺利开展,为幼儿健康、全面发展奠定良好的基础。  相似文献   

Experimental and Numerical Analysis of a Novel Display Case Design: Case Study of the Renovated Anne Frank House     

Karin Kompatscher  Bart Ankersmit  Edgar Neuhaus  Marcel A.P. van Aarle  Jos W.M. van Schijndel  Henk L. Schellen 《文物保护研究》2020,65(5):262-284

ABSTRACT

Many museums are housed in historic buildings, sometimes the building itself is part of the museum collection. Creating a stable environment by providing a nearly constant temperature and relative humidity at correct levels decreases the risk of object degradation. Maintaining this steady indoor environment, however, increases energy consumption and risks to the historic building. Museum display cases offer a solution to the mitigation of risks to which valuable objects may be subjected by providing an extra layer of protection to indoor climate fluctuations. The Anne Frank House is a historic house museum located in Amsterdam. The museum has undergone several renovations in the last years to deal with an increase in the number of visitors to over 1.2 million a year. The original diaries and other documents of Anne Frank are permanently on display in the Anne Frank House. With the recent refurbishment the possibility arose to design a new state-of-the-art display case. This study presents the results of the experimental research related to the design, performed in-situ. The temperature and relative humidity in the new exhibition space and inside the new display cases were monitored to gain insight into the hygrothermal behavior of these controlled environments. A complementary numerical study was performed to investigate effects of dynamic climate control of the exhibition gallery and climate conditions in the display case under various circumstances. Four main conclusions are presented in this paper. The investigated display case design is able to provide a stable relative humidity environment by means of silica gel, while using an active box-in-box climate control system to create stable temperature conditions. The inner case temperature depends on the temperature supplied by the display case air handling unit. Protocols must be in place in case of malfunction or failure of the climate control system of the display case. The air handling unit of the case needs to be shut off to create a passive environment for the objects on display until necessary actions are taken. Exhibition gallery set points can be less stringent when susceptible museum objects are on display in the display case. The environments are separated and provide an opportunity for energy saving set point strategies. The last conclusion drawn is that the numerical study provides valuable insight into imposing dynamic control of set points for temperature and relative humidity in the exhibition gallery and the effect on the display case environment.  相似文献   

基于短时交通流量预测对路网微观交通仿真的研究     

张虎 《苏州市职业大学学报》2021,(1)

针对早高峰短时交通流量预测数据少、波动大的特点,提出用灰色模型进行预测。将灰色GM(2,1)改进为灰色GM(2,1,λ,ρ)预测模型,以提高预测精度。针对粒子群算法(PSO)的早熟现象,将Logistic混沌搜索嵌入到PSO算法,应用混沌粒子群算法(CPSO)寻找灰色GM(2,1,λ,ρ)预测模型最优的参数λ和ρ。结合两者提出了基于CPSO–GM(2,1,λ,ρ)的早高峰短时交通流预测模型。利用VISSIM对研究路网进行微观交通仿真,通过VISSIM–Excel、VBA–Matlab平台实现了短时交通流量预测和路网微观交通仿真数据的交互,对集成交通控制系统的架构进行了方案设计。仿真结果表明,结合流量预测的路网优于固定信号配时下的路网仿真。  相似文献   

Boundary control of a linear distributed parameter bioprocess     

Hideki Sano 《Journal of The Franklin Institute》2003,340(5):293-306

This paper is concerned with boundary control of a linear distributed parameter bioprocess. Huang's result (Ann. Differential Equations 1(1) (1985) 43) on the spectrum determined growth assumption is applied to prove that the closed-loop system becomes exponentially stable under a certain condition with respect to the feedback gain. Moreover, it is shown that the decay rate of the open-loop system is given by letting the feedback gain tend to zero.  相似文献   

数字图书馆资源的访问控制问题   总被引：2，自引：0，他引：2  

李爽 《情报科学》2002,20(12):1292-1294,1297

如何运作和管理数字图书馆庞大的信息库是数字图书馆建设过程中的一个大的挑战，其中的关键问题是如何实现对数字图书馆的访问控制问题。本文详细阐述了访问控制的概念、原理和用于数字图书馆的访问控制技术以及涉及到的相关法律问题。  相似文献   

基于PLC的焊枪摆动控制系统设计     

徐鹿眉于洋  马立君 《黑龙江科技信息》2004,(2):93-93

可编程控制器产品已标准化、模块化、系列化,在工业生产中应用越来越广泛。本文介绍了焊枪摆动系统的重要性,阐明了PLC技术在焊枪摆动控制系统设计中的具体应用。  相似文献   

Tracking control of nonlinear automobile idle-speed time-delay system via differential geometry approach     

Ting-Li Chien  Ching-Yu Hsu 《Journal of The Franklin Institute》2005,342(7):760-775

This paper is concerned with the problem of global asymptotical tracking of single-input single-output (SISO) nonlinear time-delay control systems. Based on the input-output feedback linearization technique and Lyapunov method for nonlinear state feedback synthesis, a robust globally asymptotical output tracking controller design methodology for a broad class of nonlinear time-delay control systems is developed. The underlying theoretical approaches are the differential geometry approach and the composite Lyapunov approach. One utilizes the parameterized co-ordinate transformation to transform the original nonlinear system into singularly perturbed model and the composite Lyapunov approach is then applied for output tracking. For the view of practical application, the proposed control methodology has been successfully applied to the famous nonlinear automobile idle-speed control system.  相似文献   

关于战略联盟研究现状的分析与探讨   总被引：15，自引：1，他引：15  

刘益  李垣  杜旖丁 《科学学研究》2003,21(6):626-631

在搜集整理和分析研究大量战略联盟研究文献的基础上,对现有战略联盟研究现状进行了系统的分析、归纳及总结。提出目前对于战略联盟的研究主要集中在六个方面的研究问题上。揭示了战略联盟有关研究问题间的联系,并针对每一研究问题,阐明了其主要的研究角度、研究观点、研究内容及研究结论。  相似文献